Maternal Immunity and Prevention of Congenital Cytomegalovirus Infection
نویسندگان
چکیده
منابع مشابه
Maternal immunity and prevention of congenital cytomegalovirus infection.
CONTEXT Vaccine development to prevent congenital cytomegalovirus (CMV) infection has been impeded by the uncertainty over whether maternal immunity protects the fetus. OBJECTIVE To determine whether the presence of maternal antibodies to CMV significantly reduces the risk of congenital CMV infection in future pregnancies. DESIGN, SETTING, AND PARTICIPANTS Cohort study of 3461 multiparous w...
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In order to asses congenital cytomegalovirus (CMV) infection in Korea, five hundred and seventy five pregnant women (mean age 29.5 +/- 3.8 yrs., mean gestational age at test 37.5 +/- 6.7 weeks) visiting the prenatal clinic at Severance Hospital, Seoul, Korea were studied. CMV IgG antibody was present in 96% (552/575) and IgM antibody was present in 0.7% (4/575) of the pregnant women by the thir...
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ژورنال
عنوان ژورنال: JAMA
سال: 2003
ISSN: 0098-7484
DOI: 10.1001/jama.289.8.1008